proteinaceous particles measured in a biopharmaceutical formulation with a flow imaging device using dynamic imaging particle analysis
o >5 µm image data
o <5 µm counting and sizing
Similar to the Light Obstruction the sample is pumped through a sensor. Instead of passing a laser beam images are collected from the particle and the shape of the particle is determined. Assumptions can be made that spheres are Silicone droplets and that irregularly shaped particles are of a proteinaceous nature.